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Realised by ALMS™
developer of the AIDS-HIV Reference project

Poster Session

Drug Discovery and Development

TuP-039
Ryuichi Arakawa: Analysis of Electrochemical Products and Their Fragmentations for Zotepine Assay Using On-line Electrochemistry/Electrospray Ionization Mass Spectrometry
TuP-040
Guenter Boehm: Speed vs. Sensitivity: The Influence of Peakwidth and Flow Rate on Sensitivity in UHPLC-MS for Bioanalytical Quantitation
TuP-041
Ben Bolanos: Equilibrium Dialysis LC/ESI-MS for Characterizing Protein-Ligand Interactions
TuP-042
Marie-Paule L. A. Bouche: Swift and Simultaneous Determination of Darunavir (TMC114) and Ritonavir in Human Plasma Using LC-MS/MS
TuP-043
Brigitte Agnes Buscher: Quantitative Analysis of a Recombinant Protein (Tenecteplase, 60 kDa) in Rat Plasma Using LC-MS/MS
TuP-044
Gabriela Myriam Cabrera: Electrospray Ionization Mass Spectrometry of Lanostane-type Triterpene Acids
TuP-045
Lisa Jane Calton: Collision Induced Dissociation for the Identification of Drug Metabolites Using UPLC/oa-Tof Technology.
TuP-046
Jose Castro-Perez: A High Duty Cycle Parallel Approach for Metabolite Identification Using Alternating Collision Energy Scans MSe with a QTof Instrument and Data Mining Algorithms
TuP-047
Diane Cho: Mining for Metabolites Using a Linear Ion Trap Mass Spectrometer
TuP-048
Filip Cuyckens: The Use of LC-ICP-MS and LC-ESI-MS for the Metabolite Profiling and Identification of a Bromine Containing New Anti-TB Compound
TuP-049
Kaat De Wagter: Elucidation of In Vitro Metabolic Pathways Using Ion Trap Mass Spectrometry: From Methoxy-(tertiary)-butyl Substituents to Carboxylic Acids
TuP-050
Mira Victoria Doig: Quantitative Method for the Determination of Naltrexone and 6-β-Naltrexol in Human Plasma
TuP-051
Lorne M. Fell: Improving the Metabolite Identification Process with Efficiency and Speed
TuP-052
Michael Groessl: The Binding of Ruthenium(III) Anticancer Complexes to Human Serum Proteins: An ESI-MS Study
TuP-053
Vilma Habrdova: Newly Synthetized Potential Antifungal Substances: Basic Mass Spectral and NMR Data
TuP-054
Petia Dimitrova Hadjieva: GC/MS Analysis of Bulgarian Crataegus oxycantha Flowers, Leaves and Fruits Ethanol Extracts
TuP-055
Katja Heinig: Column-switching Liquid Chromatography Tandem Mass Spectrometry Analytics for Cytochrome P450 Inhibition Assays
TuP-056
Gerard Hopfgartner: High-throughput Analysis of Low Molecular Weight Compounds by MALDI on a Triple Quadrupole Mass Spectrometer
TuP-058
Sian L. Jenkins: Higher Throughput Metabolic Stability Determination
TuP-059
James Kapron: FAIMS and Highly-selective Reaction Monitoring in an LC-MS/MS Method for Clenbuterol in Urine
TuP-060
Carlos Fernandes Lopes: Determination of Trans-resveratrol in Human, Rat and Dog Plasma Using a Validated Method
TuP-061
Jana Malakova: Determination of Galanthamine and Its Metabolites in Rat Liver Tissues Using HPLC with Fluorescence and Mass Spectrometric Detections
TuP-062
Louis Maljers: The Impact of the "Reversed Energy Ramp" (RER) Scan Function on Metabolite Identification at or Below the 1µM Level on a Triple Stage Quadrupole Instrument
TuP-063
Scott Martin: Tracing the Origin of UV Peaks that Obstruct Rat Urine Metabolism Studies Using Accurate Mass ToF MS
TuP-064
Stephen McClean: A Mass Spectrometric Approach to the Characterisation of Novel Peptides from Amphibian Venom
TuP-065
Heather Clare Meigh: Using ACD Labs Software to Facilitate Drug Metabolite Identification Processes.
TuP-066
Agata Motos: Development and Application of a General and Rapid LC/MS Method for Initial Metabolism Studies in Early Adme Pre-development
TuP-067
Kazuyoshi Nozaki: Formation and Detection of Reactive Metabolites of Telenzepine Using a Radiolabeled Compound, Trapping Agent and LC/MS Technique
TuP-068
Julian Phillips: Identification and Characterization of GSH Conjugates Using Automated Data Dependent Precursor Ion MS3 Analysis on a Linear Ion Trap Mass Spectrometer
TuP-069
Pascale E. A. Proost: Evaluation of Ion Trap, Linear Ion Trap and Hybrid Triple Quadrupole/Linear Ion Trap Instrumentation for Their Use in The Elucidation of Metabolite Profiles Derived from In Vitro Metabolic Incubations
TuP-070
Anne Ryager: Structural Elucidation by Mass Spectrometry in the Pharmaceutical Industry; What Can You Achieve by LC-MSn
TuP-071
Martin Sims: Investigations into the Use of Headspace-SPME Combined with GC-MS in the Determination of Trace Level Impurities in APIs
TuP-072
Anders Sonesson: Rapid Screening of In Vitro and In Vivo Metabolites of Barusiban Using UPLC with Q-Tof Detection
TuP-073
Karel Stegman: NanoLC-MS/MS - Detection of Small Neuropeptides
TuP-075
Jason X. Tang: Characterization of CMD-193, a Calicheamicin-anti-Lewis Y Monoclonal Antibody Conjugate Using MS Based Methods
TuP-076
Lester Taylor: High Throughput Metabolic Stability Assay Using a Linear Ion Trap Mass Spectrometer
TuP-077
Ari Tolonen: Comprehensive In Vitro Interaction Assay with Cocktail Approach: Thirteen Probe Reactions for Nine Major CYP450 Enzymes in a Single LC/MSMS Run
TuP-078
The-Minh Tu: In Vivo Pharmacokinetics Following an Intravenous Cassette Dosing as a Screening Tool
TuP-079
Eric van der Horst: Validated LC-photospray-MS/MS Method for the Quantitative Determination of Cortisol and 6β-hydroxycortisol in Human Urine
TuP-080
Henk van Hal: Mass Defect Filtering and Other Software Approaches to Locate Drug Metabolites in UPLC-MS/MS Data without the Aid of Radiolabels
TuP-081
Emmanuel Varesio: The Application of MALDI for Metabolites Identification in Biological Matrices
TuP-082
Viktor Vorisek: Newly Synthetized Potential Antineoplastic Substances. Basic Mass Spectral and NMR Data
TuP-083
Hoan Vu: Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry as an Affinity Screen to Identify Binding Ligands from Natural Product Extracts
TuP-084
Sam Wainhaus: New Approaches to Rapid Pharmacokinetic and Metabolic Screening in Early Drug Discovery Using UPLC-MS/MS
TuP-085
Amina S. Woods: The Role of Proteomics and Bioinformatics in the Design of Novel Therapeutic Agents to Prevent NMDA Receptor-mediated Neurotoxicity
TuP-086
Ying Xu: Behavior of β-carboline Toward Nucleosides, Nucleobases and Oligonucleotides in Electrospray
TuP-087
Richard Zuiderent: FAIMS and H-SRM for LC-MS Method Selectivity in Drug Analysis
TuP-088
Gabriela Zurek: Complete Characterization of ML3403 Metabolites from Liver Microsomes Using QTOF and LC-SPE-cryo NMR/MS
TuP-LB3
Margaret Antler: Why is Automating the Determination of Molecular Ions Using Automated Approaches so Hard and How Might it be Used?